Health

Long-running inflammation may reshape the heart years before symptoms

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Inflammation that builds for years

A study published on September 21 finds that chronic inflammation, the low-grade kind tied to stress, lifestyle, mental health and socioeconomic conditions, may change the heart long before symptoms appear. People with the highest inflammation levels faced a 43% greater risk of heart attack and related cardiac events. Researchers say the message is that risk does not begin the day a patient arrives in an emergency room; it accumulates through years of strain, poor sleep and untreated conditions.

What the study suggests for prevention

The work adds to a run of findings linking everyday conditions to heart disease. On September 20, a separate team reported that eight common preservatives used in processed foods were associated with substantially higher rates of high blood pressure and cardiovascular disease. A review of more than 153,000 adults, also published this month, found that calcium and vitamin D supplements, taken alone or together, do little to prevent fractures or falls in most older people, which undercuts a habit millions follow for bone health.

Testing the heart earlier

Cardiologists are using cheaper markers, including C-reactive protein, alongside standard cholesterol panels, and they are paying more attention to sleep, stress and blood sugar in patients who otherwise look healthy. The practical advice from the researchers is unglamorous: treat inflammation as a long-term risk factor rather than a one-off reading, and act on the conditions that keep it high.

Other findings this week

The same week brought two less obvious results. Stanford scientists reported that the human brain develops from two distinct cellular systems, suggesting evolution fused two ancient nervous systems with different jobs. Another group described a needle-thin brain implant that can record activity, deliver drugs and stimulate several regions through one flexible fibre; it has been tested in mice so far. Neither changes care today, but both show how fast the tools used to study and treat the nervous system are changing.

Source: ScienceDaily, Journal of the American Medical Association